ISO 24276-2006 PDF

Full title and description

Foodstuffs — Methods of analysis for the detection of genetically modified organisms and derived products — General requirements and definitions. This International Standard gives general definitions, requirements and guidelines for the analysis of genetically modified organisms (GMOs) in foodstuffs and related matrices, and describes how to use and relate the applicable sampling and analytical standards for nucleic‑acid and protein based methods.

Abstract

ISO 24276:2006 specifies how to use sampling strategy standards (EN/TS 21568), nucleic acid extraction (ISO 21571), qualitative nucleic‑acid analysis (ISO 21569), quantitative nucleic‑acid analysis (ISO 21570) and protein‑based methods (ISO 21572), and their relationship in GMO analysis of foodstuffs. It includes laboratory set‑up guidance, method validation requirements, method descriptions and test report content. An amendment (Amd 1:2013) updates/clarifies some elements of the original text.

General information

• Status: Published (confirmed / under periodic review by ISO).
• Publication date: February 2006 (ISO edition 1).
• Publisher: International Organization for Standardization (ISO).
• ICS / categories: 67.050 — General methods of tests and analysis for food products.
• Edition / version: Edition 1 (2006); amended by ISO 24276:2006/Amd 1:2013.
• Number of pages: 16 (main ISO publication); amendment published as a separate 2013 document.

Key bibliographic and lifecycle information as recorded by ISO and national bodies.

Scope

Specifies the way to apply and relate the suite of standards used for detection of GMOs and derived products in foodstuffs — covering sampling strategies, extraction procedures, qualitative and quantitative nucleic‑acid assays and protein‑based methods — and provides general definitions, laboratory requirements, method validation principles, method descriptions and reporting requirements. While established for food matrices, the guidance may be applied to seeds, feed and environmental plant samples.

Key topics and requirements

• Definitions and terminology for GMO analysis.
• How to apply sampling strategy standards (EN/TS 21568) to laboratory testing.
• Guidance on nucleic‑acid extraction and preparation (ISO 21571) and protein‑based methods (ISO 21572).
• Framework for qualitative (ISO 21569) and quantitative (ISO 21570) nucleic‑acid assays and their interrelationships.
• Laboratory set‑up and contamination control recommendations for GMO testing.
• Method validation requirements and performance characteristics to be reported.
• Recommended content and format for test reports to ensure traceability and comparability.

Typical use and users

Used by food‑testing laboratories, method developers, accreditation bodies, regulatory agencies, research institutions and food industry quality/control units for establishing consistent, validated approaches to sampling, extraction, analysis and reporting of GMO testing results. It supports harmonised interpretation and comparability of qualitative and quantitative GMO data.

Related standards

Standards referenced or closely related include: EN/TS 21568 (sampling strategies), ISO 21571 (nucleic acid extraction), ISO 21569 (qualitative nucleic‑acid analysis), ISO 21570 (quantitative nucleic‑acid analysis), ISO 21572 (protein‑based methods). ISO/TC 34/SC 16 is the responsible technical committee. The standard is published alongside its amendment ISO 24276:2006/Amd 1:2013.

Keywords

GMO detection, foodstuffs, nucleic acid analysis, protein methods, sampling strategy, method validation, laboratory requirements, ISO 24276, genetic modification, test report.

FAQ

Q: What is this standard?

A: ISO 24276:2006 is an International Standard that provides general requirements, definitions and guidance for methods used to detect genetically modified organisms and derived products in foodstuffs.

Q: What does it cover?

A: It covers how to apply and relate sampling strategies, nucleic‑acid extraction, qualitative and quantitative nucleic‑acid assays and protein‑based methods, plus laboratory setup, validation and reporting principles for GMO analysis in food and similar matrices.

Q: Who typically uses it?

A: Accredited testing laboratories, regulatory bodies, food industry quality/control teams, method developers and accreditation assessors use this standard to ensure consistent, validated GMO test work and reporting.

Q: Is it current or superseded?

A: The original ISO 24276 was published in February 2006 and was amended in April 2013 (ISO 24276:2006/Amd 1:2013). ISO records indicate the publication remains in the ISO catalogue and has been subject to periodic confirmation/review. Users should check the ISO catalogue or their national standards body for the very latest lifecycle status or any subsequent withdrawals/revisions.

Q: Is it part of a series?

A: Yes — ISO 24276 is the general requirements/definitions document within a suite of standards addressing GMO analysis; it is explicitly linked to ISO 21569, ISO 21570, ISO 21571, ISO 21572 and related EN/TS sampling guidance.

Q: What are the key keywords?

A: GMO detection, foodstuffs, nucleic acids, protein methods, sampling, validation, laboratory setup, test reporting, ISO 24276.